Leptin Functions Peripherally to Regulate Differentiation of Mesenchymal Progenitor Cells
نویسندگان
چکیده
منابع مشابه
Leptin functions peripherally to regulate differentiation of mesenchymal progenitor cells.
Leptin functions through a well-documented central neuroendocrine pathway to regulate bone mass. However, the ability of leptin to modulate bone mass through a peripheral mechanism has been debated due to conflicting in vitro results and lack of sufficient in vivo models. We utilized mice with LoxP sites introduced into the long-form leptin receptor (ObRb) gene to determine how leptin regulates...
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ژورنال
عنوان ژورنال: STEM CELLS
سال: 2010
ISSN: 1066-5099,1549-4918
DOI: 10.1002/stem.432